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TPK-70.28

PKB-number: PKB66
Definition: The pseudoknot of SELEX-isolated inhibitor (ligand 70.28) of HIV-1 reverse transcriptase
Organism:
Abbreviation: TPK-70.28
RNA type: Aptamers
Keywords: SELEX; reverse transcriptase; HIV
EMBL number:
Submitted by: A.P.Gultyaev ( A.P.Gultyaev@Biology.LeidenUniv.nl)
Supported by: Sequence comparison
References: [1] Burke D.H. et al. (1996). J. Mol. Biol. 264:650-666.
Comment: The pseudoknot belongs to the so-called "Tuerk-type" pseudoknot (TPK). The pseudoknot is supported by covariations in the family of SELEX ligands that inhibit reverse transcriptase activity.
Stem sizes:
Loop sizes:
3 5
2 4 7
Position Paired:
27-29; 41-43
32-36; 51-55
Bracket view of structure:
         20        30        40        50
     #    |123456789|123456789|123456789|123456789
     $ 20 CAAGAACCGGACGGGUGAGAACCGAGACAAACACCCACCA=59
     % 20 :::::::(((::[[[[[::::))):::::::]]]]]::::

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© final design and maintenance: F.H.D.(Eke) van Batenburg; 1999-6-1 PKB00066.html